1. Our bias, stated plainly

Aminova is our product. We built it for optimization clinics — TRT and hormone, peptide, GLP-1 and medical weight loss, longevity, IV therapy and med spas — and it is unapologetically shaped around that. That focus is a genuine advantage in those clinics and a genuine disadvantage outside them.

We are also newer than the other three. That means a smaller install base and a shorter track record. If your buying criterion is "the safest, most established option with the biggest community", that is a legitimate criterion and it does not point at us.

2. Healthie — best for nutrition, coaching and programme-led care

Healthie is strongest where care is delivered as a structured programme with a lot of client engagement between visits: dietitians, nutrition practices, health coaching, and virtual-first chronic-care programmes. Its client engagement tooling, food journaling and group programme features are genuinely good and well ahead of most clinical EHRs.

It also has a mature API and developer ecosystem, which matters if you intend to build your own front-end experience on top. Choose Healthie if your practice is programme- and coaching-led, or if you have engineering resource and want a platform to build against.

3. OptiMantra — best for integrative practices with complex billing

OptiMantra is well established in integrative, functional and HRT practices and is broad — charting, scheduling, inventory, labs, billing. It handles superbills and insurance workflows more comfortably than most cash-pay-first platforms, which matters if you are a hybrid practice billing some visits to insurance.

It is a mature, feature-dense system, and that cuts both ways: more capability, and a heavier interface to learn and configure. Choose OptiMantra if you run a hybrid insurance and cash-pay integrative practice and want breadth over polish.

4. Practice Better — best for solo and small wellness practices

Practice Better is popular with solo practitioners and small wellness, nutrition and functional practices, and is generally the easiest of the four to get running on your own. Protocols, client portals and programme delivery are strong, and pricing is approachable at the low end.

Its clinical depth is lighter — it is built more for wellness and coaching workflows than for a practice prescribing controlled substances and managing compounded inventory. Choose Practice Better if you are a solo wellness or nutrition practitioner who wants to be live this week.

5. Aminova — best for prescribing optimization clinics

Aminova is built around what an optimization clinic actually does all day: prescribe, dispense, track and re-order. E-prescribing with EPCS for controlled substances is core rather than an integration, because a TRT clinic prescribes testosterone as its main activity. Inventory carries lot and expiry tracking for compounded and temperature-sensitive product. Memberships and cash-pay recurring billing are native, not bolted on.

Two things are structurally different. First, the patient app is white-labelled under your clinic's brand rather than the vendor's — patients download your clinic, not ours. Second, pricing is a flat fee per clinic rather than per provider, so adding staff does not increase the software bill.

Choose Aminova if you run a prescribing optimization clinic — TRT, peptides, GLP-1, longevity — and you are tired of assembling an EHR, a payment processor, a booking tool, a texting tool and a separate app into something that half-works.

6. Where these four actually differ

Most feature grids are useless because everyone ticks every box. The differences that decide the purchase are narrower: how pricing scales (per provider versus per clinic), whether controlled-substance prescribing is native, whether the patient app carries your brand or the vendor's, and whether inventory understands lots, expiry and cold chain.

Everything else — charting, scheduling, forms, telehealth, messaging — all four do competently. If a demo spends its time on those, you are being shown the commodity part.

7. How to actually choose

Take your three most common visit types and ask each vendor to run them end to end in a live demo, on your data, with you driving. Count the clicks. Then ask each for a total monthly figure including every module you need, with your current headcount and with one more hire.

Finally, ask all of them the same compliance question: will you sign a BAA, and what happens to my data if I leave. The answers vary more than you would expect, and both matter far more than any feature on the grid.

8. Frequently asked questions

Is Aminova a Healthie alternative?
For prescribing optimization clinics, yes. For nutrition, coaching and programme-led practices, Healthie is the stronger fit and we would say so on a call. The two products are aimed at genuinely different practices rather than competing head-on.

What is the main difference between Aminova and OptiMantra?
Focus and pricing model. OptiMantra is broader and handles hybrid insurance billing more comfortably. Aminova is narrower, built specifically around prescribing, dispensing and recurring cash-pay care, and priced flat per clinic rather than per provider.

Which is best for a TRT clinic?
The deciding factor is controlled-substance prescribing. A TRT clinic prescribes testosterone constantly, so EPCS should be native rather than an add-on, and your inventory needs to track lots and expiry. Evaluate every option against that first — it eliminates more candidates than anything else.

Do any of these include a white-label patient app?
This is one of the clearest differences. Most platforms give patients the vendor’s app with your logo inside it. Aminova ships the app under your clinic’s own brand. If patient experience is part of how you differentiate, ask each vendor to show you exactly what a patient downloads.

How should I compare pricing across these platforms?
Never compare headline prices. Ask each vendor for the all-in monthly total with every module you actually need, at your current headcount, then ask what it becomes with one additional provider. Per-provider pricing and unbundled modules are where the real difference appears.